Take care of the ball
Purdue's defense has turned a corner since the start of Big Ten play. The Boilermakers lead the conference in scoring defense, in league games, allowing just 65.3 points per game.
Their overall field-goal percentage defense has been solid (5th in Big Ten games) but they are 9th in 2-point and 3-point percentage defense in conference play.
However, the defense has thrived on turnovers. Purdue leads the Big Ten in turnovers forced during conference play (14.3 per game). Michigan basketball, on the other hand, leads the Big Ten in turnovers (given away) with 13.1 per game.
It's the most disruptive defense in the conference against the offense that's been the worst at taking care of the basketball, so keeping the turnovers under control will be huge for U-M.